2012 International Scientific Working Group

The mission of the International Scientific Working Group was to develop the 2012 Global Scientific Strategy: Towards an HIV Cure and the accompanying Full Recommendations. Following the launch of the strategy document in July 2012, the group has now officially been dissolved, but continue to cooperate with the IAS as an international pool of experts.

The team of over 30 leading scientists, representing various disciplines, areas of work and institutions, began drafting the scientific strategy in early 2011. Using a bottom-to-top approach, with scientists defining the priorities collaboratively, the Global Scientific Strategy is designed to provide a robust and innovative scientific roadmap towards an HIV cure.

The International Scientific Working Group was divided into four subgroups:
  1. Virological mechanisms of HIV persistence
  2. Immunological mechanisms and compartments involved
  3. Pre-clinical & translational tools: Quantification, characterization & monitoring HIV reservoirs
  4. Clinical trials


Subgroup 1: Virological mechanisms of HIV persistence

  • Ben Berkhout, University of Amsterdam, The Netherlands
  • Carine Van Lint, University of Brussels, Belgium
  • David Margolis, University of North Carolina at Chapel Hill, USA - co-chair
  • Eric Verdin, University of California, San Francisco, USA
  • Mario Stevenson, University of Miami Medical School, USA
  • Matija Peterlin, University of California, San Francisco, USA
  • Monsef Benkirane, Insitute of Human Genetics, France
  • Tae-Wook Chun, NIAID/NIH, USA - co-chair

Subgroup 2: Immunological mechanisms and compartments involved

  • Alan Landay, Rush University Medical Center, USA
  • Brigitte Autran, Immunity-Cancer-Infection Federative Research Institute, France
  • Guido Poli, San Raffaele University and Scientific Institute, Italy - co-chair
  • Guido Silvestri, Emory University School of Medicine, USA
  • Melissa Churchill, Burnet Institute, Australia
  • Nicolas Chomont, VGTI- Florida, USA - co-chair
  • Steven Deeks, University of California, San Francisco, USA - co-chair

Subgroup 3: Pre-clinical and translational tools: Quantification, characterization & monitoring HIV reservoirs

  • Amalio Telenti, University of Lausanne, Switzerland
  • Christine Rouzioux, University Paris Déscartes/Hospital Necker, France
  • Javier Martinez-Picado, irsiCaixa Foundation, Spain
  • Jim Mullins, University of Washington, USA
  • John Mellors, University of Pittsburgh, USA
  • Michele Di Mascio, NIAID/NIH, USA
  • Sarah Palmer, Karolinska Institute, Sweden - co-chair*
  • Sharon Lewin, The Alfred Monash University and Burnet Institute, Australia - co-chair
  • Una O’Doherty, University of Pennsylvania, USA

Subgroup 4: Clinical trials

  • Alain Lafeuillade, General Hospital, France - co-chair
  • Ann Woolfrey, Fred Hutchinson Cancer Research Center, USA
  • Christine Katlama, Pitié-Salpêtrière Hospital, France
  • Frank Maldarelli, NCI/NIH, USA
  • Jean-Pierre Routy, McGill University, Canada - co-chair
  • John Zaia, Beckman Research Insitute of City of Hope, USA
  • Martin Markowitz, Aaron Diamond AIDS Research Center, USA
  • Santiago Moreno, Hospital Ramón y Cajal, Spain

*University of Sydney, Australia (updated affiliation)